Skinspire Laser&Skin Clinic

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Stubborn Fat

Losing fat in certain areas is harder than others. Stubborn fat in places like shoulders, thighs, and bellies require powerful and effective technology for treatment.

What is Stubborn Fat

Stubborn fat is hard to shed and subcutaneous fat is one example. It’s easy to gain but tough to lose. Once the body burns off excess regular fat, it targets excess subcutaneous fat. This fat has high tissue density and is strongly linked to insulin sensitivity. Stubborn fat has the lowest blood flow of all types of fat that can be consumed.

Stubborn fat is difficult to lose because it has more α-adrenergic receptors, which inhibit lipase and fat burning. Normal fat tissue has more β-adrenergic receptors, which promote lipase activity and fat burning. Stubborn fat is also more sensitive to insulin and has lower blood flow compared to visceral and intramuscular fat.


There are internal and external causes of our body storing stubborn fat.

External Factors

1. Poor Sleeping Patterns

Poor sleep can cause hormonal issues that prevent fat burning, leading to weight gain. Staying up late, sleeping poorly, and prolonged stress can increase cortisol levels, encouraging the storage of stubborn fat. Adjusting sleep patterns is key to weight control.

2. Eating Habits

Consuming excessive amounts of sugary, high calorie, or fatty foods leads to weight gain. Additionally, a high carbohydrate diet that includes refined carbohydrates (such as white rice, noodles, and bread) can cause spikes in blood sugar and insulin levels, resulting in stubborn fat formation.

3. Lack of Exercise

A sedentary lifestyle leads to unused energy becoming fat, which is then stored as stubborn fat.

4. Ageing

The body primarily uses energy through metabolism, physical activity, and digesting food. As we age, our metabolism naturally slows down, making it more difficult to lose weight if we don’t exercise regularly. Testosterone and growth hormone levels can also decline with age, further contributing to a lower metabolism.

Internal Factors

1. Sensitive to Insulin

Insulin can make fat store faster, especially in sensitive areas like the waist, abdomen, and thighs.

2. Slow Blood Flow at the Fat Tissue

Slow blood flow in fat tissue can affect fat metabolism. Different parts of the body have varying blood flow, which means they have different fat metabolism. Areas with slow blood flow have lower fat metabolism and fewer lipolysis-promoting hormones, such as catechol. Stubborn fat cells with low blood flow can avoid being eliminated and transported out.

3. Lower Body Temperature
Lower Body Temperature can slow down fat burning and encourage storing of stubborn fat due to its lower temperature compared to the rest of the body.

4. Oestrogen

Oestrogen is a factor that increases the activity of α-adrenergic receptors, contributing to stubborn fat. Women generally have more oestrogen than men, which can result in more stubborn fat for them.


In Skinspire Laser&Skin Clinic, you can simply lose fat at specific body parts by the Lipodissolve Injection.

Lipodissolve injection offered by Skinspire Laser&Skin Clinic is a safe and effective way to reduce localized fat, such as double chins, chubby faces, arms, and legs. This treatment boosts fat metabolism, aids digestion of fat cells, and tightens and lifts skin.

How does Lipodissolve Injection work

The injection targets and breaks down fat cells, which are then eliminated by the body through the lymphatic system.


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