Radiofrequency (RF) technology has long been a cornerstone of non-surgical anti-aging treatments.
Thermage® is a well-established RF system, while XERF represents Cynosure’s latest advancement in RF-based skin tightening.
Although both utilize RF energy, they differ in applicator design, energy delivery, treatment depth, and clinical strategy.
1. Applicator Design & Coverage
Thermage®
- Square-shaped applicator with strong skin contact
- Well-suited for uneven areas such as the forehead and periocular region
- Designed for comprehensive and precise full-face tightening
XERF
- Larger rectangular applicator
- Covers broader areas per treatment pass
- Particularly effective for cheeks, jawline, and neck
- Allows more efficient treatment sessions

2. Energy Technology
Thermage® | Monopolar RF
- Single-frequency RF energy
- Targets the dermal layer
- Induces immediate collagen contraction and long-term regeneration
- Typically performed once per year
XERF | Multi-Mode RF System
- Multiple RF output modes
- Adjustable treatment depth based on skin condition
- More uniform energy distribution with enhanced comfort
- Suitable for both corrective treatment and ongoing maintenance

3. Clinical Focus & Patient Selection
- Thermage® is generally recommended for patients with more advanced skin laxity seeking long-lasting tightening
- XERF is well-suited for early to mid-stage aging and patients prioritizing comfort and natural-looking improvement
In clinical practice, XERF is often used 3–6 months after Thermage to help maintain and prolong results.
Why Choose Skinspire?

Skinspire Laser & Skin Clinic is committed to offering cutting-edge anti-aging technologies and tailored treatment solutions. Our highly experienced medical team delivers customized aesthetic care to help you achieve your anti-aging and skin rejuvenation goals.
We prioritize both safety and results, ensuring an effective and comfortable treatment experience. If you are interested in anti-aging treatments, contact Skinspire Laser & Skin Clinic for professional consultation and personalized treatment planning.
Skinspire Laser & Skin Clinic – Irvine
📍 2500 Alton Pkwy Ste 201, Irvine, CA 92606
Skinspire Laser & Skin Clinic – Rowland Heights
📍 1330 Fullerton Rd #202-203, Rowland Heights, CA 91748
📞 949-818-8188
🌐 www.skinspire.us
📧 [email protected]
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